Donor Testing
Donor Testing Laboratory
This department of eight employees operates 18 hours a day, six days a week, including holidays, and is responsible for ensuring that all required and confirmatory testing is completed for approximately 95,000 allogeneic, autologous and apheresis donations collected at Hoxworth Blood Center in FY09.
This department also ensures that any potentially infectious or sub-standard product is quarantined and discarded to prevent release to general inventory.
Hoxworth Blood Center no longer performs required donor testing on site. Indiana Blood Center serves as the testing facility for Hoxworth Blood Center and has done so since 1998.
Current Food and Drug Administration (FDA) and AABB required testing, in addition to other supplemental testing, is performed to detect/determine:
ABO/Rh;
Antibody to:
Human Immunodeficiency Virus (HIV) Types 1/2, HIV-1 subtypes O and M;
Hepatitis B Core (HBC) Antigen;
Human T-Lymphotrophic Virus (HTLV) Types I & II; Hepatitis C Virus (HCV);
Syphilis (T. pallidum);
Chagas Disease (T. cruzi)
Presence of Alloantibody to Red Cell Antigens
Antigen to:
Hepatitis B Virus (HBV) Surface Antigen
Nucleic Acid Testing (NAT) for viral RNA for:
HCV;
HIV-1;
West Nile Virus (WNV);
Supplemental Testing:
Cholesterol (for donors wishing to track their non-fasting cholesterol levels).
Infectious Disease Testing Information
The Donor Testing Laboratory receives many questions concerning the dates of infectious disease testing. The following table is a brief synopsis on the history and current status of infectious disease testing performed at Hoxworth Blood Center.
|
Infectious Disease Testing |
Date Test First Implemented |
Current Testing Implementation |
|
Hepatitis B Surface Antigen (HBS) |
Early 1970's |
Abbott PRISM HBS 9/21/2006 |
|
Human Immuno deficiency Virus (HIV) Type 1 |
5/1/1985 |
Abbott PRISM HIV O Plus (Types 1&2, O, M) 12/1/2009 |
|
Hepatitis B Core Antibody (HBC) |
7/1/1986 |
Abbott PRISM HBC 9/21/2006 |
|
Alanine Aminotransferase (ALT) Testing |
10/14/1986 |
Discontinued 10/1/2004 |
|
Human T-Lymphotrophic Virus (HTLV) Type I |
3/1/1989 |
Abbott PRISM HTLV Types I/II
4/1/2008 |
|
Hepatitis C Virus (HCV) |
5/6/1990 |
Abbott PRISM HCV 9/11/2007 |
|
HIV p24 Antigen Testing by EIA |
4/29/1996 |
Discontinued 6/1/2003 |
|
HCV by NAT |
4/28/1999 |
HIV/HCV NAT combined in one assay 6/1/2003 |
|
HIV by NAT |
1/3/2000 |
|
|
West Nile Virus (WNV) by NAT |
7/1/2003 (under IND protocol) |
Licensed test implemented 4/1/2006 |
|
Syphilis |
1960's |
Antibody to T. pallidium in 1/31/1991 |
|
Chagas |
12/1/2007 |
Antibody to T. cruzi |
EIA = Enzyme Immunoassay
ELISA = Enzyme-linked Immunosorbent Assay
PRISM = Chemiluminescence Immunoassay
NAT = Nucleic Acid Testing
In FY09, this laboratory also performed over 50,000 discrete Quality Control (QC) tests on randomly selected products. By testing randomly selected products, Hoxworth Blood Center is able to ensure that products meet the minimum quality assurance specifications set by the FDA and AABB. The result is that physicians can better manage blood transfusion therapy for their patients knowing that a standard minimum dose is what will be infused.
Daily operations are managed by Jody Hupp, MLT(ASCP), Asst. Director. The Donor Testing Laboratory is under the direction of Gregg Boothe MS, MT(ASCP)SBB, Division Director, Laboratories. The Medical Director is Patricia Carey, MD.
Contact Information
To contact the Donor Testing Laboratory dial 513-558-1200. Press 9 for a listing of departments. Press 6 to be connected with the Donor Testing Laboratory.
Request or Discuss Donor Test Results
Donor test results will only be released to the donor with proper identification.
To request a copy of your test results, or to discuss the meaning of a test result, please contact Laurel Wysocki, Manager, Donor Quality Assurance. Click on her name for email or, to speak in person, please dial 513-558-1317.
Updated 12/8/09
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